Delayed diagnosis of a primary intraosseous squamous cell carcinoma: A case report
Abdelkarim Ahmed Z., Elzayat Ahmed M., Syed Ali Z., Lozanoff Scott,
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( Abdelkarim Ahmed Z. ) - University of Hawai’i Department of Anatomy, Biochemistry and Physiology
( Elzayat Ahmed M. ) - Insurance Hospital Department of Oral and Maxillofacial Surgery
( Syed Ali Z. ) - Case Western Reserve University School of Dental Medicine Department of Oral and Maxillofacial Medicine and Diagnostic Sciences
( Lozanoff Scott ) - University of Hawai’i Department of Anatomy, Biochemistry and Physiology
Abstract
Primary intraosseous squamous cell carcinoma is a rare malignant central jaw tumor derived from odontogenic epithelial remnants. Predominantly, it affects mandible, although both jaw bones may be involved. This report describes a 60-year-old man who was initially misdiagnosed with a periapical infection related to the right lower wisdom tooth. After four months, the patient presented to a private dental clinic with a massive swelling at the right side of the mandible. Panoramic radiographs and advanced imaging revealed a lesion with complete erosion of the right ramus, which extended to the orbital floor. A biopsy from the mandibular angle revealed large pleomorphic atypical squamous cells, which is the primary microscopic feature of a poorly differentiated squamous cell carcinoma.
키워드
Carcinoma, Squamous Cell; Mandible; Delayed Diagnosis; Computed Tomography, X-Ray; Magnetic Resonance Imaging
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